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How Many Injections are Needed for IVF Treatment?
In-vitro fertilisation (IVF) is the medical process of fertilising an egg by sperm in a test tube. IVF is a nexus of multiple procedures assisting fertility and child conception.
IVF has been labelled as the most efficient form of assisted reproductive technology (ART). It can be done using a couple’s own eggs and sperm. Other ways include using eggs, sperm,
or embryos from an anonymous or a known donor. It is best to seek guidance from a fertility specialist to achieve your goal of family planning. Consult doctors, communicate,
and discuss the prospects with experienced IVF partners to help you set your tasks before undergoing the procedure. Doctors prefer to use IVF injections for pregnancy to stimulate
ovaries and treat infertility in women who have problems ovulating on their cycles.
Prime IVF Fertility Centre is the leading infertility treatment provider and the best IVF centre in Delhi ncr. It has an experienced team which will provide you the best medical care in infertility.
What to Expect from IVF Injections?
IVF injections for pregnancy are injectable drugs that help stimulate ovulation. These medications help your doctor to control ovulation from the beginning of the treatment cycle.
During this entire period of ovulation, the doctor will monitor the ultrasound and blood work, primarily estradiol levels and growth of the oocytes till maturation. This will help the doctor to adjust the dosage as and when required. You can perceive the following observations while undergoing this procedure:
- Changes in body and increase in appetite: Hormonal injections can affect the weight and basal metabolic rate (BMR) of your body. You may also notice an increase in your hunger and satiety levels. This might be due to the effect of some medications taken during the treatment. If you gain weight at a rapid pace, seek medical advice at the earliest.
- Changes in behavior like feeling emotional and distracted: Hormonal injections can affect your emotional quotient leading to an emotional outburst suddenly. IVF treatment can be overwhelming for some parents. They may feel emotional and distracted from their usual activities.
- Gastrointestinal (GI) related side effects: Constipation and diarrhoea are the frequently observed side effects of hormonal injections. You should consume a healthy diet that includes fibre and drink plenty of water.
- Psychological effects of stress and anxiety: Hormonal injections and fertility treatment as a whole can be frustrating and you start observing symptoms of stress and anxiety. Regular consultations with your practitioner and doing stress-relieving activities like meditation and yoga are proven highly useful in alleviating the symptoms.
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How Many Injections are Required for IVF?
IVF treatment requires medications that are usually given via injections either subcutaneously (directly into the fat just under the skin) or intramuscular (directly into the muscle).
Depending on the course of specific treatment and cycle, a patient may receive up to 90 shots per cycle with a frequency of 1–2 injections per day. These medications
might include gonadotropins, i.e., follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which stimulate the ovaries to develop mature follicles and ultimately eggs.
Another hormone, progesterone is naturally produced after ovulation in usual cases. In some patients undergoing IVF, insufficient levels of progesterone are observed and hence,
supplementation is prescribed. The supplementation starts around the time of egg retrieval or ovulation and continues until the pregnancy-produced progesterone maintains the levels itself.
How to Make IVF Injections Easier?
The process of IVF poses multiple challenges and injections are one of them, especially in women with low tolerance to pain. Various methods and practices can be adapted to ease any pain and related discomforts.
- Educate yourself about the process, related side effects and how you can manage them symptomatically.
- Talk to any specialist that conducts cognitive behavioural therapy (CBT) to overcome the phobia of needles and injections. This is because it includes up to 90 injections during the entire treatment. Learn the tricks of pinching the skin or pulling it tight to experience the similarity with the injection pinch.
- Use an ice pack application or heating pad to numb the site. For the subcutaneous shot, 15–30 seconds of icing is enough to numb the nerves; however, for the intramuscular shot, using a heating pad for approximately 10–15 minutes will relax the muscles and make them more pliable for the injection.
Which Time is Best for IVF Injections?
IVF Treatment in Delhi process includes stimulating injections of gonadotropins to stimulate the ovaries. Recent studies have shown that specific time is not a dependent
factor for stimulation injections and there is no difference in the delivery rate when they are taken either in the morning or evening. A clinical trial observed the difference in
certain aspects of hormone levels of peak estradiol or progesterone, endometrial thickness, number of mature oocytes, fertilisation stage, or blastocysts obtained when the gonadotropins
were administered in AM (morning) and PM (evening) groups.
There was no difference in the initial or baseline vitamin D levels and the quantity of gonadotropins used in the medicine. The trend of higher implantation rate, higher chemical pregnancy rate, and higher clinical pregnancy rate was observed in the AM group. In addition to this, you must take into account the duration of injections, i.e., injections at the same time slot every day. This practise may vary depending on the combination of injections that are prescribed to you and menstrual cycle variation.
Fertility injections take approximately 8–14 days from the initiation of hormonal medications until eggs are mature and ready to retrieve. Once the process of IVF injection begins, you must maintain a healthy lifestyle and avoid vigorous exercise to ensure better egg quality.
What are the Side-effects of IVF Injections?
Like with any other medicine, IVF stimulation injections also may cause some common side effects which are listed below. It is important to understand and discuss these with your doctor before the treatment is initiated. Seek professional help if you need any assistance in monitoring and managing them.
- Headaches, night sweats, and hot flashes
- Abdominal pain, bloating, and nausea
- Upset stomach and discomfort
- Changes in cervical mucus
- Temporary visual disturbances (blurred vision)
- Dizziness and frequent mood swings
- Tenderness in the breast
- Skin redness, soreness, or bruise at the injection site
- Irritability and restlessness
- Overstimulation of ovaries termed ovarian hyperstimulation syndrome (OHSS)
Every drug may or may not cause these side effects and experiencing these will be different for every patient. Some of the effects may be witnessed as mild symptoms.
The symptoms might be temporary and may subside without causing any further complications. Nevertheless, seek immediate medical assistance if the symptoms persist for
a longer duration and do not resolve within a few days with your discomfort level increasing on a daily basis.
Depending on the type of injection, you may have to mix and prepare your medicine before injection. Injection sites may also vary on the type of injection you are giving yourself.
Your nurse will provide you with specific instructions for the injections you need to take. As you continue your IVF cycle, you will have morning appointments starting day 5 of your injections. You will also have blood work done at these visits. Your doctor will order more ultrasounds and blood tests as needed each day. Your doctor may also need to change the dose of your medication.
You will need to be available by phone during your IVF cycle. Your nurse may need to contact you with important information about your medications and appointments. It is imperative that you have an identifiable voicemail, as we will need to reach patients during the processs, and cannot leave a message without an identified voicemail.
On average, it takes about eight days to two weeks from when you begin taking the hormone medication until your eggs are mature and ready for retrieval.